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Fluorescein and ICG Angiography
 

 The abnormal blood vessels associated with macular degeneration are traditionally identified using fluorescein angiography.  The dye is injected into the blood and pictures are taken with a filter to see the fluorescence filling the blood vessles.  Abnormal blood vessels glow and leak.  Sometimes the leakage is poorly localized or blocked by blood or pigment and the source of the abnormal blood vessels cannot be found.  ICG angiography was developed to help find the source of blood vessels in such cases.  The ICG dye emits infrared light which can be seen though hemorrhage and pigment.  In addition, it is a larger molecule that pools in the blood vessels beneath the retina, facilitating visualization of the source of the abnormal blood vessels.  When ICG angiography shows a "hot spot" away from the center of vision (fovea), then laser treatment may be effective despite the poorly defined membrane on fluorescein angiography.  Unfortunately, hot spots are uncommon. 

Laser Treatments

Fluorescein Angiography

ICG Angiography

Photodynamic Therapy (PDT)

Pharmacologic Therapies  

Macular Translocation Surgery

Submacular Surgery

Retinal Transplantation

Radiation Therapy

Genetics

Nutrition  

Other Treatments